Tag Archives: Animal Fat

Cholesterol Levels May Not Measure Cardiac Risk

After writing about the inaccuracies of using cholesterol as the primary marker for heart disease in “Saturated Fat and Animal Fat—Further Vindication”, I came across this article from HealthDay discussing a recent study of cholesterol levels and heart disease.  This is further support for why simply lowering cholesterol numbers is not the answer to heart disease.  In the study, “Lipid levels in patients hospitalized with coronary artery disease: An analysis of 136,905 hospitalizations in Get With The Guidelines,” from American Heart Journal, researchers found that almost 75% of patients hospitalized for heart attacks had cholesterol levels that fell within normal healthy guidelines.  While Fonarow, the lead researcher on the study, states in an interview, “Cholesterol is only one part of the heart risk picture,” in the study he concludes “These findings may provide further support for recent guideline revisions with even lower LDL goals.”

I continue to contest that cholesterol should not be the only and may not be the best indicator of heart disease risk, and that lowering the guidelines may not be the answer.  (Also, please notice the financial disclosures at the bottom of the study and the numerous pharmaceutical companies that contributed.)

Here’s the article from HealthDay on the study:

Cholesterol Levels May Not Measure Cardiac Risk
Normal readings showed up in many who had heart attacks, study shows

Posted January 16, 2009

By Ed Edelson
HealthDay Reporter

FRIDAY, Jan. 16 (HealthDay News) — Nearly three-quarters of patients hospitalized for heart attacks had cholesterol levels indicating they were not at high risk for cardiovascular trouble, a new, nationwide study shows.

The finding points to the possibility that current guidelines on cholesterol levels should be changed, said study author Dr. Gregg C. Fonarow, a professor of cardiovascular medicine and science at the University of California, Los Angeles. His report appears in the current issue of theAmerican Heart Journal.

“The LDL cholesterol range at which people have heart attacks shouldn’t be regarded as normal,” Fonarow said.

LDL cholesterol, the “bad” kind, collects to form plaques that can eventually block arteries. Guidelines compiled by the U.S. National Heart, Lung and Blood Institute set an LDL cholesterol blood level target of 130 milligrams per deciliter for people with no cardiovascular disease or diabetes and 70 for those at high risk because of factors such as obesity, smoking and high blood pressure.

But the study of nearly 137,000 Americans hospitalized for heart attacks between 2000 and 2006 found that about 72 percent had LDL levels below 130 on admission, while 17.6 percent had LDL levels below 70.

“People with LDL cholesterol levels in the 100 to 130 range may feel they are at low risk,” Fonarow said. “In this study, there was nothing normal about having an LDL reading of 100.”

The study also looked at levels of HDL cholesterol, the “good” kind that helps prevent artery blockage. Current guidelines recommend an HDL level of 60 or higher, but the study found levels below 40 in 54.6 percent of the heart attack patients.

Only 1.4 percent of patients met the recommendation for both an LDL level of 70 or lower and an HDL reading of 60 or higher, Fonarow noted.

The current National Cholesterol Education Program guidelines were first set in 2001, and were updated in 2004. The NHLBI is expected to review those guidelines in the near future, Fonarow said.

“My opinion, based on the totality of the evidence that has come out, is that it is likely that there will be important revisions to the guidelines, but that should be determined by the individual advisory groups that will be writing them,” he said.

In its update of the guidelines, the NHLBI called for more use of measures such as physical activity and weight loss to reduce the risk of heart attack and other cardiovascular problems.

Cholesterol is only one part of the heart risk picture, Fonarow said. Risk climbs higher with age, especially for men and for those with close relatives who have had cardiovascular conditions.

“The good news is that as much as 80 percent of the risk factors are under individual control and are modifiable,” Fonarow said. “You can’t control your family history, age or sex, but you can keep your blood pressure low, exercise and modify your lifestyle in other ways to reduce risk.”

While calling the study “excellent,” Dr. Manesh Patel, an assistant professor of medicine at Duke University, added, “The problem is that this is a snapshot, but we’re not sure we know all the risk factors and how they interplay.”

The researchers did not measure blood levels of other molecules involved in cardiovascular disease, such as the inflammation biomarker C-reactive protein and lipoprotein(a), he said.

But it’s quite possible that the cholesterol guidelines will be changed, Patel said. “Ongoing studies have led to getting the LDL level to 100 and then to 70,” he said. “As more randomized trials come out, there may be further changes.”

Saturated Fat and Animal Fat—Further Vindication

If you’re like me and consume (gasp!) saturated fat and animal fat, you most likely spend a lot of time explaining to friends and family that think you are crazy that these fats are good for you.  With decades of incorrect nutrition information on fats fed to the public by almost all mainstream nutrition sources, it be difficult if not virtually impossible to have people listen to you without really knowing your facts.  Here’s some support.Good_calories_bad_calories

Good Calories, Bad Calories: Fats, Carbs, and the Controversial Science of Diet and Health by Gary Taubes is a must read!  Taubes is an award-winning science writer and in his book he lays out over 450 pages of scientifically referenced information to support why fat and saturated fat are not bad nor the main cause of heart disease, and how refined carbohydrates are actually the culprit in heart disease, diabetes, and obesity.

He does an amazing job presenting the evidence behind how once the world of science “concludes” something as fact, “rational” scientists lose all objectivity from peer pressure that they will be marginalized and ridiculed for challenging the status quo.  Facts from scientific study that contradict the theory of the day are completely dismissed-it’s like the scientists can not even see them.  This is the tragedy of current science and how the mainstream nutrition information of today could be so wrong about all fat, but particularly saturated fat, and refined carbohydrates.

At your next social event or conversation when you are defending butter, eggs, and even bacon in your diet, here’s some information (which Taubes lays out) that might help until you read his book. Besides your own experience of how good you feel when you consume saturated fat (the best barometer and argument that exist), let’s discuss some misinformation about saturated fat, cholesterol, and heart disease to start.

Firstly, “total cholesterol” is not the best indicator of heart disease.  Many things influence cholesterol: exercise, weight loss/gain, stress, hormones, medications and alcohol.  We now know HDL, LDL, and triglycerides are better warning signs (but even so LDL is very misleading).  However, when studies were conducted on fat in the diet and heart disease, the only thing measured was total cholesterol, and consequently incorrect assumptions were made-that had consequences for decades.

He explains that while any diet that causes you to lose weight will lower total cholesterol some what, it does not lower the rates of heart disease and can even increase it when starchy carbs and sugars are chosen over good fats.  When studies were done in the 1940s and 1950s the subjects lost weight and had a minor drop in cholesterol, but lower cholesterol levels were never shown to be associated with a reduction in heart disease risk (in fact many studies showed the opposite).

While saturated fats can raise LDL that carry cholesterol,
it is carbohydrates that elevate VLDL.
This VLDL carries triglycerides (and some cholesterol). Drs. Albrink, Man, and Meigs found that
elevated triglycerides were far more common than high cholesterol in
coronary-heart-disease. When a patient is put on a low fat diet, it might lower
LDL a little but it will raise VLDL disproportionately, the much more
significant risk factor for heart disease.

Even though there is still some question on LDL being “bad”
as there are many different densities of LDL that are not measured and is
controversial today, let’s assume for this discussion that some LDL is
bad. And what we do know is that
high HDL is associated with a lower risk of heart disease. Carbohydrates lower HDL (and raise
triglycerides). Monounsaturated fat (the most commonly known source is olive
oil) increases HDL and lowers LDL cholesterol. Taube states, “The observation that monounsaturated fats
both lower LDL cholesterol and raise HDL also came with an ironic twist: the
principle fat in red meat, eggs, and bacon is not saturated fat, but the very
same monounsaturated fat as in olive oil.
The implications are almost impossible to believe after three decades of
public-health recommendations suggesting that any red meat consumed should at
least be lean, with any excess fat removed.

“Consider a porterhouse steak with a quarter-inch layer of
fat. After broiling, this steak
will reduce to almost equal parts fat and protein. Fifty-one percent of the fat is monounsaturated, of which 90
percent is oleic acid. Saturated
fat constitutes 45 percent of the total fat, but a third of that is stearic
acid, which will increase HDL cholesterol while having no effect on LDL.
(Stearic acid is metabolized in the body to oleic acid, according to Grundy’s
research). The remaining 4 percent
of the fat is polyunsaturated, which lowers LDL cholesterol but has no
meaningful effect on HDL. In sum,
perhaps as much as 70 percent of the fat content of a porterhouse steak will
improve the relative levels of LDL and HDL cholesterol, compared with what they
would be if carbohydrates such as bread, potatoes, or pasta were consumed. The remaining 30 percent will raise LDL
cholesterol but will also raise HDL cholesterol, and will have an insignificant
effect, if any, on the ratio of total cholesterol to HDL. All of this suggests that eating a porterhouse
steak in lieu of bread or potatoes would actually reduce heart-disease risk,
although virtually no nutritional authority will say so publicly. The same is true for lard and bacon.”

Next Taubes goes on to describe in detail how carbohydrates,
particularly high starchy foods, refined flour products, sugar, and
high-fructose corn syrup are the main cause of heart disease, diabetes, and
obesity. He explains how some of
these foods raise glucose but others such as high-fructose corn syrup raises
triglycerides and well as increases the oxidation of LDL particles—leading to
increased risk of atherolsclerosis and heart disease.

I highly suggest reading Good Calories, Bad Calories. Taube spent 5 years on the research for
this book, and his conclusions were due to the information he uncovered not
preconceived notions. The science
and history of nutrition is fascinating and enlightening.



The information provided on this website is for informational purposes only. It is not intended as a substitute for advice from a physician or other health care professional.
Every effort is made to make sure this website is accurate and as up to date as possible.